CHEWABLE ASPIRIN ???

28 Feb

Contrary to information published in the Daily Mail, Tuesday 23rd February 2010. It is NOT necessary to buy ‘chewable’ aspirin to gain the benefits of self administered ‘immediate aspirin’.

It is, however, imperative that the aspirin deliver its platelet inhibition as quickly as possible. This is best achieved by chewing and swallowing a soluble aspirin as opposed to taking solid dose aspirin.

In order to find out which presentation worked fastest, researchers in Texas asked 12 volunteers to take a 325-mg dose of aspirin in three different ways; by swallowing a tablet with water, by chewing the tablet for 30 seconds before swallowing it, or by drinking water with an effervescent aspirin dissolved in it. Each subject tried all three methods on an empty stomach on different days. Scientists monitored blood levels of aspirin and its active ingredient, salicylate, at frequent intervals, and they also measured thromboxane B2 (TxB2), an indicator of platelet activation that drops as platelets are inhibited.

By all three measurements, chewed aspirin worked fastest , taking only 14 minutes for the chewed tablet to produce maximal platelet inhibition; it took effervescent aspirin 16 minutes and the swallowed solid dose tablet 26 minutes.

IF YOU HAVE A CHOICE, DO NOT USE ENTERIC COATED ASPIRIN. IT WILL ACT MORE SLOWLY, EVEN IF CHEWED.

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IMPORTANT NOTE: IF YOU NEED TO TAKE AN EMERGENCY DOSE OF ASPIRIN YOU MUST DIAL 999 FOR AN AMBULANCE FIRST – AND THEN IMMEDIATELY CHEW AND SWALLOW ONE 300mg SOLUBLE ASPIRIN.  If in doubt speak to your Doctor.

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