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What does the ASPIRIN FOUNDATION say about early aspirin?

7 Feb

The ISIS-2 trial, co-ordinated in Oxford, reported on randomised aspirin and thrombolytic treatment after infarction in over 17,000 patients and the CAST trial involving 21,000 stroke patients gave evidence of a reduction in mortality when aspirin was given early after the onset of symptoms. The ISIS-2 trial showed that aspirin given within 0-4 hours of a heart attack reduced risk by 25% and if given within 5-24 hours after symptoms, reduced risk by 21%.

A report by the British Heart Foundation now recommends early therapeutic intervention with aspirin and rapid transferral of patients to hospital for intravenous thrombolysis with what is often described as a ‘clot buster’ drug.

Members of a family or work colleagues are thus ideally placed to begin early treatment with aspirin in patients with suspected acute MI, since aspirin can easily be given straight away. The recommended dose of aspirin given at this stage is 150mg (half a standard aspirin tablet) and the patient should be advised to chew the tablet to aid absorption. You must confirm that the patient is conscious and able to swallow before recommending the early or immediate administration of aspirin. Unconscious patients or those unable to swallow should not be given any medication by mouth but referred to emergency professional treatment immediately.

The advantage of this therapeutic strategy is that if the pain turns out to be simply muscular, aspirin will not have been inappropriate, whereas if the pain does arise from an infarct, ‘immediate’ or ‘early’ aspirin intervention may well save a life or prevent disability.

The Aspirin Foundation
Aspirin at Christmas
11.12.2001

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IMPORTANT NOTE: IF YOU NEED TO TAKE AN EMERGENCY DOSE OF ASPIRIN YOU MUST DIAL 999 FOR AN AMBULANCE FIRST – AND THEN IMMEDIATELY CHEW AND SWALLOW ONE 300mg SOLUBLE ASPIRIN.  If in doubt speak to your Doctor.

‘Good Health Insight’ – Daily Mail, Tuesday February 22nd 2000

6 Feb

In Sweden men and women over the age of 35 never go out without a little white pill in their wallet. It could mean the difference between life and death in the event of a heart attack. The Swedes have taken on board the message of heart specialists that the simple aspirin could have a major impact on surviving a coronary. At the first sign of severe chest pains, Swedes call an ambulance and then pop a tablet in their mouths.

‘Good Health Insight’ – Daily Mail, Tuesday February 22nd 2000

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IMPORTANT NOTE: IF YOU NEED TO TAKE AN EMERGENCY DOSE OF ASPIRIN YOU MUST DIAL 999 FOR AN AMBULANCE FIRST – AND THEN IMMEDIATELY CHEW AND SWALLOW ONE 300mg SOLUBLE ASPIRIN.  If in doubt speak to your Doctor.

Do Not Wait and Die!

26 Jan

Do Not Wait and Die!

If you suffer from chest pain, seek help immediately by dialling 999 or 112.  Do not wait and die.

Early use of 300mg of Aspirin has been proven to improve survival and outcome from myocardial infarction and is used by Paramedics in UK ambulance services as a first line treatment. Early administration of aspirin can produce major benefits and is safe to use in patients who are not allergic to aspirin and do not have ulcer problems. Carrying aspirin and knowing what to do in a cardiac emergency may help save your life or that of another”

Dr Iain Robertson-Steel, MRCGP DIMC RCSEd, formerly Consultant Medical Director of a major UK Ambulance Service and currently a Health Board lead on Unscheduled Care supports the early administration of aspirin to appropriate patients; he carries aspirin himself for emergency personal use.

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IMPORTANT NOTE: IF YOU NEED TO TAKE AN EMERGENCY DOSE OF ASPIRIN YOU MUST DIAL 999 FOR AN AMBULANCE FIRST – AND THEN IMMEDIATELY CHEW AND SWALLOW ONE 300mg SOLUBLE ASPIRIN.  If in doubt speak to your Doctor.

Pre-Hospital Aspirin: NHS

23 Jan

…. only four of 133 patients received aspirin at home. Possibly the number noted was falsely low owing to prior regular aspirin therapy. However, the benefits attributed to aspirin in acute myocardial infarction are in connection with the use of 150 mg or more being chewed at the time of the acute event. Therefore, until further information is available aspirin should be given acutely to all patients suspected of myocardial infarction, regardless of their regular treatment.

Pre-hospital opiate and aspirin administration in patients with suspected myocardial infarction
H R Wyllie, F G Dunn: BMJ 1994
Cardiac Department, Stobhill General Hospital, Glasgow

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IMPORTANT NOTE: IF YOU NEED TO TAKE AN EMERGENCY DOSE OF ASPIRIN YOU MUST DIAL 999 FOR AN AMBULANCE FIRST – AND THEN IMMEDIATELY CHEW AND SWALLOW ONE 300mg SOLUBLE ASPIRIN.  If in doubt speak to your Doctor.

Life saving early and immediate aspirin: too little too late

23 Jan

Life saving early and immediate aspirin: too little too late

There are a number of reasons why the earlier aspirin is given the greater the potential for saving life: Platelet emboli have been found within the coronary circulation in subjects whose death has been ‘‘sudden’’. If taken early enough, aspirin could cause disaggregation of the platelets in an embolus, could reduce the growth of any such emboli, and could prevent the development of a thrombus and its stabilisation by the incorporation of fibrin. Platelet aggregation and embolisation are highly active in unstable angina and aspirin is of greatly enhanced efficacy in this situation. Evidence suggests that the reduction in relative risk for subsequent non-fatal MI or death after aspirin administration is greater for unstable angina (51%) than it is for MI (25%). Antiplatelet agents also play an important role in the management of patients with non-ST segment elevation MI. There is a peak in the occurrence of MI in the early morning between about 04.00 and 10.00 h and this coincides with an increased sensitivity of platelets to aggregating agents. The readiness with which a patient is likely to call an ambulance or a doctor, and the availability of help during these hours, is probably less than later in the day. Furthermore, it is of relevance to ‘‘self help’’ in this situation that in the US Physicians trial it was found that the reduction in MI caused by aspirin treatment was significantly greater during the early morning (59%) than during the later part of the day (34%). Most patients with an ST segment elevation MI are likely to receive thrombolytic therapy. There is a pronounced heightening of platelet activity after thrombolysis, and prior treatment with aspirin abolishes the excess in re-infarction that otherwise follows fibrinolysis. It is essential therefore that aspirin is given before fibrinolytic therapy is commenced.
The earlier fibrinolysis is started the better, and the delegation of this to paramedics has been recommended.

The best way to ensure that aspirin has first been taken is for the patient to have taken it him/herself.

Postgrad Med J 2008
Life saving early and immediate aspirin: too little too late.
Malcolm Woollard, Peter C Elwood, Gareth Morgan.

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IMPORTANT NOTE: IF YOU NEED TO TAKE AN EMERGENCY DOSE OF ASPIRIN YOU MUST DIAL 999 FOR AN AMBULANCE FIRST – AND THEN IMMEDIATELY CHEW AND SWALLOW ONE 300mg SOLUBLE ASPIRIN.  If in doubt speak to your Doctor.

A headache for paramedics?

23 Jan

A headache for paramedics?

Excerpt from the Emergency Medical Journal 2001.

Aspirin has been shown to be beneficial after a myocardial infarction and for other acute coronary syndromes. However, variances in the proportion of patients with suspected iscaemic heart disease given aspirin in different ambulance services indicates the need for a re-emphasis on the importance of this treatment. A standard protocol for all UK ambulance services should be devised that minimises the number of contraindications to aspirin and otherwise requires its administration to all patients with acute coronary syndromes or suspected myocardial infarction. Regular, standardised audits of compliance should also be conducted and their results widely disseminated.

Pre-Hospital aspirin for suspected myocardial infarction and acute coronary syndromes: A headache for paramedics?
M.Woollard, A. Smith, P.Elwwod.

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IMPORTANT NOTE: IF YOU NEED TO TAKE AN EMERGENCY DOSE OF ASPIRIN YOU MUST DIAL 999 FOR AN AMBULANCE FIRST – AND THEN IMMEDIATELY CHEW AND SWALLOW ONE 300mg SOLUBLE ASPIRIN.  If in doubt speak to your Doctor.

Aspod featured in Woman Magazine

19 Jan

Aspod® was recently featured on the Dr Chris Clinic pages of Woman Magazine. Dr Chris Steele answered a readers question regarding heart attacks. The feature reads:

Q: We have a family history of heart attacks. I’m worried about my parents’ health. Is there any good advice I can pass onto them?
A: Buy them both an ASPOD. It’s a little device costing only £5.99, with space for two 300mg soluble aspirins. Chewing and swallowing an aspirin in the event of a heart attack can save lives.

Aspod is featured in Woman Magazine

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IMPORTANT NOTE: IF YOU NEED TO TAKE AN EMERGENCY DOSE OF ASPIRIN YOU MUST DIAL 999 FOR AN AMBULANCE FIRST – AND THEN IMMEDIATELY CHEW AND SWALLOW ONE 300mg SOLUBLE ASPIRIN.  If in doubt speak to your Doctor.

Stroke Awareness

17 Jan

Aspirin should not be taken if symptoms suggest a stroke. If aspirin is taken without medical advice at the very commencement of symptoms suggestive of a stroke and if the stroke is a haemorrhagic (bleeding) lesion, then the cerebral bleeding might be very markedly increased.

Stroke is the third most common cause of death in the UK and it is also the single most common cause of severe disability. Nationally more than 250,000 people live with disabilities caused by stroke.
a TIA (Transient Ischaemic Attack) happens when the blood supply to the brain is interrupted for a short while but then goes back to normal. A TIA may affect an arm or a leg, drooping to one side of the face, numbness down one side, or cause speech problems. It comes on suddenly and recovers completely, usually within minutes or hours and definitely within 24 hours. For one in five people, TIAs can be a warning sign that a stroke is likely to occur in the future and therefore should never be ignored. It is recommended that people apply the FAST test and act faster:

  • Facial awareness – can the person smile?
  • Has their mouth or eye drooped?
  • Arm weakness – can the person raise both arms?
  • Speech problems – can the person speak clearly and understand what you say to them?

Time to call 999 for an ambulance if you spot any one of these
signs. If someone has had a stroke then you need to ring 999 – FAST!

Aspod and ‘Immediate’ aspirin saved my husband’s life.

15 Jan

Please note: The information both here and on our site www.aspod.co.uk is supplied by doctors, pharmacists and academics who routinely use the phrase ‘soluble aspirin’. In this context the phrase ‘dispersible’ aspirin has the same meaning. Generic soluble 300mg aspirin, for use in your Aspod, is available from all UK pharmacies.

The real life story of a woman whose quick actions saved her husband’s life

” I regularly watch ITV’s this morning programme. I always take notice of the medical sections of the programme and have found it interesting to see how promoting the use of certain products has saved people’s lives. I have always thought that these people seem to be very lucky to have seen these reports and be in the right place at the right time.  (more…)

The science behind immediate aspirin

10 Jan

The science behind immediate aspirin

A summary of the supporting evidence that immediate aspirin really can save lives.

There is strong evidence that aspirin, taken during a heart attack, can reduce the size of the thrombus (clot) causing the attack [1,2] and may even cause the platelets in the clot to disperse [3,4]. Aspirin also has effects on processes other than clotting [5,6], suggesting that if taken very early in an attack, the damage to the heart could be reduced and additional lives saved.

Patients known to be at risk of a heart attack, including all persons over about 50 years of age, would be well advised to carry a few tablets of soluble aspirin at all times, and chew and swallow a tablet immediately, if they experience severe chest pain, even as they are phoning 999. (more…)